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Scripps researchers say a molecular redesign of fentanyl may preserve pain relief while reducing the deadly breathing suppression that drives overdoses.
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Retiring curator Phil Unitt's final lecture explores the people and history behind the San Diego Natural History Museum's extensive bird and mammal archive.
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Blue Line Trolley commuters were delayed Wednesday because of a tree that fell near the E Street Station in Chula Vista.
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Thousands of San Diego Gas & Electric customers were without power Wednesday following multiple outages reported across the South Bay.
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When asked whether recent redistricting efforts such as those in California and Texas amount to attempts to "rig" the 2026 midterms, survey respondents most often blamed the opposing party. However, nearly 25% of members of each party also assigned responsibility to their own leaders.
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The County Administration Building in downtown San Diego will lower its flags to half-staff and illuminate in rainbow colors this evening in honor of the late Rev. Jesse Jackson, it was announced Wednesday.
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The San Diego area should get a lull from this week's winter storms later Wednesday, before more rain arrives on Thursday.
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The North County Transit District announced Wednesday that all coastal rail service between San Diego and Oceanside will be suspended this weekend for routine railroad maintenance and major infrastructure work.
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No two senior centers are alike. We visited three very different venues in L.A. to learn how they’re changing for California’s aging population.
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The unsettled atmospheric system also generated stiff winds and widespread overnight lightning ground strikes, including one that set fire to scores of trees in Escondido, authorities said.
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